Researchers from Tokyo Medical and Dental University (TMDU) and collaborating partners have expanded the utility of a common chemical tool for biomolecular analysis. This work will facilitate precise ... The composition and function of the biomolecular corona depends on the physicochemical properties of the nanoparticle, and the composition and incubating conditions of the exposed biological system.

Understanding the Context

Biomolecular condensates are membraneless hubs of condensed proteins and nucleic acids within cells, which researchers are realizing are tied to an increasing number of cellular processes and diseases ... Researchers from Dewpoint Therapeutics published a paper “Modulating biomolecular condensates: a novel approach to drug discovery” in Nature Reviews Drug Discovery that examines the potential of ... Biomolecular condensates—droplets of proteins and RNA that coalesce and then quickly disappear from the cytoplasm of our cells—are having a moment. Faze Medicines is the third company to launch in the ...

Key Insights

Biomolecular interactions are at the core of drug discovery and development. In order to accurately determine a biomolecular interaction’s affinity, binding kinetics and thermodynamic profile, among ...